A multi-line video poker machine that allows gamblers to play any number of hands, form 1 to 100, inclusive.

A multi-line video poker machine that allows gamblers to play up to 5 hands. However, maximum coins on all five hands must be bet. Otherwise, the royal payout is shorted.

Referring to a video poker machine that allows gamblers to play one or more lines (equivalently, hands or plays) simultaneously. Multi-Line machines always deal a single video poker hand. The draw, however, can be from 1 to 100 hands, depending on the machine.
See also: 100-play, 50-play, 10-play, 3-play, 5-play.